So how can we combat Type 2 diabetes? Slow-Mag is designed to maximize mag's benefits while simultaneously minimizing its side effects. I dont do such silly things anymore. I am absolutely in the process of rewriting it, and that is my intention. Additionally, Dr. Peter is an advisor to and/or investor in the following companies: Virta Health, Hu Kitchen, Oura Health Oy, Magic Spoon Cereal, Inevitable Ventures, Salutoceuticals, Dexcom, and Supercast. Dr. Attia believes we must replace this outdated framework with a personalized, proactive strategy for longevity, one where we take action now, rather than waiting. People Lists Series Gifts. Autophagy is, as its name implies auto is self, phagy is eating so its when these cells eat themselves. Those three effectively make up three quarters of deaths of people who dont smoke. , Theres one disease, which is not really thought of as a disease, but I think of it as a continuum that is the foundation upon which all of those sit. Our staff also includes Alison Craiglow, Greg Rippin, and Corinne Wallace; our intern is Emma Tyrrell. is directly causal in disease in nondiabetics; There have been no RCTs demonstrating that better glycemic control in nondiabetics leads to better outcomes, much less using CGM; There have not been any long-term studies using CGM in nondiabetics whatsoever; Some of the interventions to reduce CGM readings (say, carbohydrate restriction) also would increase postprandial triglycerides, also associated with worse outcomes; There is therefore an unclear tradeoff between hyperglycemia and hypertriglyceridemia, and that is assuming that they are each causal for bad outcomes in healthy nondiabetics; The cutoffs for unacceptable glucose excursions by Peter Attia are not based on any evidence whatsoever and are arbitrary. To listen ad-free, subscribe to Stitcher Premium. Additionally, Dr. Peter is an advisor to and/or investor in the following companies: Dr. Peter has an impressive career, but hes an even more impressive person in real life! The purpose of comments on our site is to expand knowledge, engage in thoughtful discussion, and learn more from readers. Thats the problem that Dr. Peter and other doctors like him are trying to solve. Studying studies: relative risk vs. absolute risk. Dr. Attia received his medical degree from the Stanford University School of Medicine and trained for five years at the Johns Hopkins Hospital in general surgery, where he was the recipient of several prestigious awards, including resident of the year. I think they often get confounded. So my guess is, theres some measure around helping them become better thinkers. The only sad part is my dad said a few days ago, Yeah, the last person I grew up with and I was friends with, they died. The owner of this blog reserves the right to edit or delete any comments submitted to the blog without notice. Including a link to relevant content is permitted, but comments should be relevant to the post topic. We won. LEVITT: Yeah. Peter Attia, MD, is the President and co-Founder of the Nutrition Science Initiative (NuSI). So I dont know that I really deserve any credit. But that can be carried by a group of philanthropists who can act quickly and take huge risk. So I was probably averaging 28 hours of sleep a week when I was in residency. Theres one disease, which is not really thought of as a disease, but I think of it as a continuum that is the foundation upon which all of those sit. Can you describe how you approached your undergraduate classes at Stanford? The parallel in economics, the National Science Foundation, is the big federal funder of a lot of economists. So shes like, lets watch M.S.T.3.K. I hope you loved this episode as much as I did. Peter Attia is among the most brilliant people I've ever met, and he's succeeded in packing a life's worth of insights into this book. Hes playing the long-game and working hard to maintain the strength and overall good health hell need to continue living an active and fulfilled life even when hes over 100 years old. And lets be honest. So it wasnt one thing, Steve. And I think a lot of people get there eventually in life, but I would just say, dont be afraid of that type of exploration. and . Dr. Peter is working hard to keep his body strong and healthy functioning even into old age. But life isnt really about necessarily being the master of something. [1] [2] He is also the first person to make the round-trip swim from Maui and Lanai. So autophagy is a very important process for preventing cancer. So I embarked on a sleep experiment that went on for maybe three months where I did not sleep more than three hours a night. I mean, I probably wish I had been a bit more introspective a bit sooner. LEVITT: Oh, God. Ive never really experienced nicotine. But I still stand by the benefits of nicotine. But nobody knows you even started doing it. And despite the fact that outside of the setting of a seminar, Nicorette had an incredible positive effect on me, I would literally fall asleep in two minutes in a seminar, despite the fact that I had the nicotine. Your podcasts are like a massive gift to humanity. We care about this. Peter Attia talks with Steve Levitt about the problem with immortality, whats missing from our Covid response, and why nicotine is underrated. And then I would go to the gym and do an hour workout before that was mostly rowing machine and skipping. Glucose is such an important molecule for energy that if we were to go more than about a day and a half without eating, we would begin rapidly destroying our muscle mass in an effort to produce enough glucose to satisfy our brain, which would further impair our ability to forage for food. But my hunch is, youd know better than me, is that for things like influenza, we actually dont even know the answer, even though weve had 100 years to be thinking about that. After medical school, Attia spent five years at the Johns Hopkins Hospital in Baltimore, Maryland as a general surgery resident. This is a tragedy. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. [5] He spent two years at the National Cancer Institute (NCI) at National Institutes of Health (NIH), in Bethesda, Maryland as a surgical oncology fellow under Steven Rosenberg. Its complicated because there are lots of reagents that go into that type of testing and we dont control the origin of each of those reagents. When it comes to chronic and life-threatening diseases, Dr. Peter said it comes down to three major things: "So the big three are, in order, atherosclerotic disease so that's vascular disease, meaning heart disease and stroke. Now, all of those diseases have different effects and treatment methods, and over the last several decades, weve learned a lot about preventing and reversing them. LEVITT: And did that pay off when you went to surgery? TheDriveis hosted by Dr. Peter Attia, a Stanford/Johns Hopkins/NIH-trained physician focusing on the applied science of longevity, the extension of human life, and well-being. In fact, our conversation was so fascinating, that I decided to split it into two episodes! Theres days I guess I am. Peter Attia (born 19 March 1973) is a Canadian-American physician known for his medical practice that focuses on the science of longevity. LEVITT: Yes, so you gave me some Nicorette gum, and Ive never really smoked. And I dont think Im very good at it, Steve. I admire his dedication to becoming a kick-ass 100-year-old, and I only hope I can do the same! But it could put a slightly different interpretation on it. He is of Coptic Egyptian descent. Both of them are funded by the Arnold Foundation, with substantial ties to animal agriculture industry lobbying. I actually find a fasting sleep to be some of the most amazing because Im watching this plummeting temperature, rising heart rate variability, falling heart rate, all of those really valuable things. , I think there [are] basically three ways that we can approach dealing with this: One of these is through psychotherapy, pharmacotherapy, and then behavioral therapy, which Im an overwhelming proponent of in particular a type of behavioral therapy called Dialectical Behavioral Therapy or DBT. , My training is very specific, but now it is fundamentally organized around four pillars: Stability, strength, mitochondrial or aerobic efficiency, and anaerobic performance. , Those four main pillars focus on the different areas Dr. Peter wants to maintain good health even into old age. Peter Attia (born 19 March 1973) is a Canadian-American physician known for his medical practice that focuses on the science of longevity. And just to be clear, Im just the guy who started it and who raises the money. Please be respectful toward other contributors. Comments that harass other posters will be deleted. And when I was in high school, I became obsessed with him. To me the more important question, Steve, and the one I spend more time thinking about, is: what do you do next time around? And then I would come home and I had a ritual that I would do 400 pushups every single night in sets of 50s and then go to bed and repeat. So the other thing we always want to be optimizing around is how much fiber can you get? But the point is, without making these proactive changes, they mightve lived only until 70. A surgeon who developed metabolic syndrome himself despite the fact that he ate well and exercised often, Attia realized that our understanding of these important health issues may not actually be correct. Non-lame, weekly emails on thelatest strategies and tacticsfor increasing your lifespan, healthspan, and well-being (plus new podcast announcements). No government funds at all, is that right? Stay tuned for Wednesdays episode Part 2 of my interview with Dr. Peter Attia! Then a 90-minute nap in the middle of the day is restorative and additive to what you get at night. I rarely have a conversation with Peter in which he doesnt introduce me to something Ive never thought about before. CAUSE THE OBESITY EPIDEMIC IN THE UNITED STATES? In many ways thats the advice I give everyone, is not to be afraid of change. This magnesium features what's called an enteric coating to protect it from premature disintegration. But I just decided death would be welcome. ATTIA: Well, I think the benefits of fasting are legion. According to Tools of Titans, Attia takes 600 to 800 mg per day of magnesium, alternating between mag sulfate and mag oxide. Because for most people, the last 20 years, especially the last 10 years, are not great, both physically and cognitively. I look at my father, whos 86 and still runs and still practices medicine full time, and we do trivia contests together and hes still as good as he ever was. Its about exercising intentionally. LEVITT: The set of things hes done to his body over time, in the spirit of self-experimentation, are mind-blowing. And I think its the perfect model, which is: let the government come in when its been de-risked. Hes playing the long-game and working hard to maintain the strength and overall good health hell need to continue living an active and fulfilled life even when hes over 100 years old. Whats good about nicotine? and holds a B.Sc. So how about nicotine? Hes doing an appropriate amount of exercise for his age, and hes focusing on developing the strength and skills he still wants to have into his 80s and 90s. What type of a person is going to be safe in what type of an environment to go back to work? in mechanical engineering and applied mathematics. But it was like, You got to do it, man. Dr. Peter is the perfect person to talk to about health and longevity, and Im excited to have him on. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease) while simultaneously improving healthspan (quality of life). So after college and before grad school. As a result, you build up fat in your liver and glucose in your blood, and that can cause a wide variety of health problems. It is the one thing that makes all three of those worse, and, in its most extreme state, its Type 2 diabetes. It quickly raised more than $40 million from big-name donors to facilitate expensive, high-risk studies intended to illuminate the root causes of obesity. I could basically, within two weeks, turn you into an almost-diabetic by sleep depriving you. Dr. Peter Attia. And to this day, we still respect each other greatly. So I abandoned that one on my own. Thats a relevant detail that Im sure a few peoples eyes just rolled back in their head. He also. Explore the list of the most recommended book titles suggested by Peter Attia . And finally, the fourth thing that significantly affects our chances of getting Type 2 diabetes is stress. Were living to reach older and older ages than ever before, which is great. He is well . Peter Attia is the host of The Drive podcast and . And in particular, I dont know if youve looked at naps at all, but theres some new research that suggests that in terms of afternoon productivity, naps have an incredible impact. HOMA-IR and frailty (same study as #3 linked twice); The studies that use OGTT do not establish that glucose variability above 140 mg/dL is important; None show that the high glucose itself is causal or that reducing it via diet will improve outcomes. ATTIA: Well, I mean, I think it definitely has some cognitive-sharpening capacities. Explore the list of the most recommended book titles suggested by Peter Attia . If I just took 20 guys like you and took them from eight hours a night to four hours a night for two weeks and then did these glucose tolerance tests, I could reduce [their] glucose disposal by 50%. Hes been an engineer, a surgeon, a management consultant, and even a boxer. Which doesnt necessarily undo or undermine the results of that. It turns out that our bodies perform a lot of glucose disposal when we sleep, so sleep is incredibly important for preventing glucose from building up in our bloodstreams. And I was like, You know what? . And then you have to have a third project, which is like 75 percent done. Saturated fat and dieta postprandial triglyceridemia is associated with cardiovascular disease risk, Why lose weight to prevent covid-19 is an inappropriate and harmful message for health influencers to be sending, Mainstream, popular health gurus peddle ineffective, dangerous, and costly products that degrade physical and financial health, Why I question the objectivity of low-carb pioneers Stephen Phinney and Jeff Volek. To improve sleep, Peter Attia takes phosphatidylserine, magnesium and a supplement called Doc Parsley's Sleep Remedy (a company in which Attia invested), comprising of vitamin D, niacin, magnesium (150 mg), and a blend of tryptophan, GABA, phosphatidylserine, theanine, 5-HTP and melatonin. Our lifespan is the amount of time we live, and it is steadily growing longer. Where did this insecurity come from? My guest today is physician Dr. Peter Attia. By implication, it cannot be used to make nutrition recommendations. And theres days when that really hurts. So the other night here is a funny story, because it will come across that my daughter lives a tortured life she really does enjoy this stuff. When we eat, our bodies naturally raise our temperature its just part of the digestion process. In addition to being an accomplished physician, Dr. Peter is also a successful businessman. Its a bit of luck and its having really good people around me who are really patient, who have been able to help nurture me back to a new way of thinking about life that is unrecognizable compared to the ethos that was 10 years ago. Which is: what are those people who cant quit also incapable of doing on a day to day basis, vis vis their very rigid view of, this is the way to do things versus not. And Im still generally a somewhat rigid person. LEVITT: Thats intense. Hes one of the most intelligent, curious, compassionate people Ive ever met. And that work ethic came from this belief that I actually dont think is that healthy. Those four main pillars focus on the different areas Dr. Peter wants to maintain good health even into old age. Thank you so much for joining me today! It also has a significant effect in terms of fat oxidation. ATTIA: So there were a lot of things that were really upsetting me at the time. Ive known Peter for 10 years. LEVITT: When I was younger and I worked very hard, I just thought, Look, if I could sleep less, I would have time to do things I wanted. And so I read the literature and I embarked on a sleep experiment. Marion Nestle notes the Arnold's working relationship with a National Restaurant . LEVITT: Yeah, I mean, youve listed a bunch of things that we would want to know the answers to that we dont know the answers to. Dr. Peter Attia received his medical degree from Stanford University in 2001. Your lifespan may be longer, but your healthspan the amount of life you live in good health isnt. Attia has a chapter giving advice in Tim Ferriss' book Tools of Titans. Last week, Peter Attia wrote a criticism of Game Changers, where he presented the argument (long repeated him) that nutritional epidemiology is fundamentally flawed. from Stanford University and holds a B.Sc. Im involved in a coronavirus study now, that were trying to get off the ground, thats looking at the long term impact of immunity. So, Ive done a lot of different things and that makes me a master of nothing. And so I want to challenge you to do that. And while learning to manage stress and overcome trauma may not be the only thing it takes to prevent Type 2 diabetes, it will definitely increase your odds of staying healthy longer. Aside from preventing chronic diseases like Type 2 diabetes, how can we extend our healthspans to become, as Dr. Peter put it, kick-ass 100-year-olds? to do just that, Dr. Peter structures his exercise around four main pillars: My training is very specific, but now it is fundamentally organized around four pillars: Stability, strength, mitochondrial or aerobic efficiency, and anaerobic performance. Dr. Peter Attia. Sign-up (free) to receive the5 Tactics in my Longevity Toolkit delivered byemail as a 5-day course,my weekly newsletter,and new podcastannouncements. Lets talk a little bit about the difference between lifespan and healthspan because theres a really key distinction between them. But what was it? What Happened To Peter Attia. Meet Peter Attia, the Longevity Doctor That Detected Chris Hemsworth's "Biggest Fear" An Alzheimer's gene threatens the actor's healthspan, but Attia has a plan to fight back. But theyre not really set up to do big, big thinking. Poor, poor waitress. He is the Co-founder and Chief Medical Officer of the fasting app Zero. ATTIA: I mean, if Im going to be critical, its not what we did in the first moment. Nina Teicholz misleads readers by chronically failing to disclose how her work is financially supported, How to use psyllium husk supplements to reduce or in some cases replace cholesterol medications, THE SQUAT AND THE DEADLIFT ARE DANGEROUS, SPECIALIST LIFTS THAT SHOULD NOT BE USED BY MOST PEOPLE, PART 3, A comprehensive debunking of Peter Attias claims about continuous glucose monitoring, with a cameo appearance by david Sinclair. is incredibly risk averse. LEVITT: And it sounds like youre doing it all with private money. ", https://en.wikipedia.org/w/index.php?title=Peter_Attia&oldid=1139971534, Stanford University School of Medicine alumni, Articles with unsourced statements from February 2023, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 17 February 2023, at 19:54. LEVITT: You have given a lot of advice already about nutrition and health. I know Im inspired to increase my healthspan in addition to my lifespan, and I hope you are too! Im sure anyone who did something at a high level, whether it be playing the piano or doing anything, once theyre so far past their prime, they look back and go, I dont think I appreciated what it took to get there.. But the point is, without making these proactive changes, they mightve lived only until 70. ATTIA: I actually this is probably one that has changed less than most in the past decade. Note this may include abusive, threatening, pornographic, offensive, misleading or libelous language. But I love that about you, that youre willing to change your mind. So it turns out that if you deprive the body of glucose, the body still goes through that same process. So, nicotine leads to the up-regulation of an enzyme I wont bother to name that is beneficial to how the muscles can utilize fat for energy and how the fat cells refrain from just taking more fat in as storage. Now that Im concerned with longevity, that type of working out is totally unnecessary. So you went to Stanford and got your medical degree there and then you did your residency at Johns Hopkins. Whats so good about being in ketosis? He is an ultra-endurance athlete, compulsive self-experimenter, and one of the most fascinating human beings I know. ATTIA: No. Stay up-to-date on all our shows. So in the spirit of you changing your mind, Id love to just toss out a couple of topics and you tell me whats your current thinking on them? This episode is informative, and I know youll get a lot of value from it. So, I think it puts N.I.H. Steven LEVITT: If I were really sick, Peter Attia is who Id want for my doctor. However, theres one disease that underlies all three of these. Now hes a physician focused on the science of longevity. And I do that in academic seminars and its incredibly embarrassing. Born: 1973. Apparently Peter and his buddy Gary Taubes just love themselves some crappy pseudoscience. And these days I spend virtually no time in nutritional ketosis. Sign-up (free) to receive the5 Tactics in my Longevity Toolkitdelivered by email as a 5-day course. And theres no getting around that. Workout and Diet. 200mg is relatively minor, but he supplemented for the sake of avoiding muscle cramps. Hes one of the most intelligent, curious, compassionate people Ive ever met. [8][9] Ive been enjoying them very much, If you want to know how to live longer, and how to live better, you should be listening to Peter. LEVITT: So can you talk about ketosis a little bit and what that means? And caffeine blocks that. Now, on with the show. Thanks, interesting.This is a lot of psyllium to swallow. And I ended up having a C.T. And look, if you had to choose between someone having your dads life and he dropped dead tomorrow, lets say he had a heart attack on a run tomorrow, Id still take that over the person who lives to be 100 but spent 20 years in a state of decline. ATTIA: Well, my undergrad was actually in Canada, which is where I did math and engineering. Mass vaccination would interfere with this a lot. Its great to live until youre 90 or 100 years old, but if you spend the last 20 or 30 years in so much pain or with a neurodegenerative disease like Alzheimers, youre not really enjoying those last few decades. pick up the tab to really finish it, because this is a multi-year experiment. And also, what hes going to talk about in this documentary is really complicated. Freakonomics is a registered service mark of Renbud Radio, LLC. And we differentiate that form from the one that we evolved with by calling it nutritional ketosis. Peter Attia is a Canadian-born doctor who focuses on the science of longevity. It was really an interesting thing to watch. Below this, it has no benefit, above this, its toxic. One half of all Americans are on that spectrum. , So how can we combat Type 2 diabetes? He remains unbiased and sticks to what the science indicates while also willing to experiment on himself. The second thing I would say is: really do not consider sunk costs in your career. Fish Oil. I want to be able to hop over a three-foot fence. And when my daughter was born, I ended up getting a type of medical test that had a finding that no one in their mid-thirties should have. I basically had the worst headache of my life for the next three months. He is licensed in Texas (S8803), California (A96452), and New York (281406-1). And so for six months, Ive been doing something that was probably a really bad idea as well. So, if we can stop eating a few hours before bedtime, well get better sleep, our bodies will process the glucose we consume, and we can avoid Type 2 diabetes. You have to have a second project which youve actually done, but you pretend that you havent done it. While it's easy for me to say, I implore you to keep fighting back and never . A SIXTEEN-ARTICLE POWERBOMB. Peter Attia, M.D. But Im not the person thats actually going to do these studies. Its a very expensive study for one year. I mean, this is not an unethical thing to do. Comments including unnecessary profanity will be deleted. And to me, we want to minimize that gap, right? He spent two years at the National Institutes of Health as a surgical oncology fellow at the National Cancer Institute, where his research focused on immune-based therapies for melanoma. So, if we can turn off the phones well before bedtime, well find it a lot easier to fall asleep. But I have to say, hes also completely, totally insane. on their work. He also receives speaking honorariums from organizations, including hospitals and health-related businesses, when he is asked to speak on longevity, metabolic-related topics, athletic performance, and his personal experience working in medicine. And the more adenosine you accumulate, the more you fatigue. And that, to me, is where I get shocked at what Id call the failure of medicine in this dimension to provide us with the answers that, if we had known a lot more about other kinds of infectious diseases, we probably could have been a lot smarter. Or that we overeat? document.getElementById( "ak_js_2" ).setAttribute( "value", ( new Date() ).getTime() ); Copyright 20122023 PA IP, LLC. Our staff also includes Alison Craiglow, Greg Rippin, and Corinne Wallace; our intern is Emma Tyrrell. ATTIA: No, I think its the hardest job. Dr. Attia is medical doctor who focuses on the science behind living a longer, healthier life. His practice also focuses on elements such as diet, sleep, exercise, and, physiological aspects that promote But the muscles could use it. Thank you so much for joining me today! Its also the one that seemed the most conflicted. So the former is one molecule of something called glucose and one of fructose bound together. What did your day look like? In addition to being an accomplished physician, Dr. Peter is also a successful businessman. Both of them are funded by the Arnold Foundation, with substantial ties to animal agriculture industry lobbying. Why didn't you address what Nina has brought up? The heart could use it. So I just generally say try not to eat too much before bed. Why werent we immediately engaging in a whole bunch of experiments that would very rapidly get us answers to questions that would enable us to decide what to do? So the brain could use it as a glucose substitute, and it would offset 50 to 60 percent of its glucose requirement. So my hours from 11:00 at night until like 5:00 in the morning, in a cold apartment. [4] So maybe some combination of those two things would be helpful as a person navigates their way. . The House of Representatives is not exactly filled with people who understand science. ATTIA: Ive come a long way since then, Steve. So I think the whole boxing thing came from an insecurity. ATTIA: Yeah, I mean, most of these viruses are actually benign enough. In 2014, Attia founded Attia Medical, PC, a medical practice focusing on the applied science of longevity and optimal performance. @bariweiss. He also has a B.Sc. Peter Attia, MD Intends To Win The Centenarian DecathlonHere's How August 2022 Huberman Lab Exercise, Nutrition, Hormones for Vitality & Longevity August 2022 Jocko Podcast Overcoming Stress, Sleep Deprivation, and the Darkness with Peter Attia January 2017 The Tim Ferriss Podcast Fasting, Metformin, Athletic Performance, and More (#398) And actually, my model ended up working really well, but I was basically threatened that Id be fired if I ever did it again. Comments containing language or concepts that could be deemed offensive will be deleted. Which diseases are killing people the most and what to do about it. Its not about exercising more, especially as he gets older. Criticism and skepticism can be far more useful than praise and unflinching belief. Dr. Peter Attia is a physician focusing on the applied science of longevity. But when we sleep, its best for our bodies to be cold when we sleep cooler, we get more rejuvenating sleep. And during all of this intentional exercise, Dr. Peter has one thing in mind: his Centenarian Olympics. Youll be able to read more about this in Dr. Peters book when it comes out, but for now, I can tell you that the Centenarian Olympics is a series of activities that Dr. Peter wants to be able to do when he turns 100. But I certainly didnt appreciate at the time what it was doing to my health. Dr. Peters goal is to reduce those early deaths as much as possible. But do you have advice for young people who are trying to find their path in the world? And I want you to interrupt me every time you have a question.. How many other concussions I had, I dont know. [3] Career [ edit] Peter Attia was born on 19 March 1973 in Toronto, Ontario, Canada. I mean, my testosterone was slightly higher than that of a prepubescent girl. LEVITT: And how much fasting does a person have to do to start getting those benefits? Dr. Peter says there are four main ways to do it. But not too far behind it is cancer. In fact, Dr. Peter recommended to stop eating about three hours before bedtime. Part of the practice includes nutritional biochemistry, a field that deals with supplements.