Essex Woodlands Health Ventures, City (cities) where offices are located: Palo Alto, CA; Houston; New York; London; Shanghai, Fund size and status: More than $2.5 billion under management across eight funds (4), Current fund: $900 million Fund VIII, closed 2009 (4), Current biopharma portfolio companies: Acura Pharmaceuticals, Biotoscana, Bioventus, Catalyst Biosciences, Chroma Therapeutics, Corium, Curis, Echo Therapeutics, Elusys Therapeutics, Horizon Pharma, IntegenX, LightSciences Oncology, Medicinova, Molecular Partners, Open Monoclonal Technology, Oraya Therapeutics, Revance Therapeutics, Symphogen, Ziopharm Oncology, City (cities) where offices are located: Cambridge, MA; New York; Palo Alto, CA, Fund size and status: $2.6 billion under management across seven funds, Current funds: $450 million Venrock VII, closed July 2014 and intended to invest in technology and healthcare companies; $350 million Venrock VI, closed 2010 (5), Current biopharma portfolio companies: Acceleron Pharma, Achaogen, Anacor Pharmaceuticals, Ariosa Diagnostics, Avalanche Biotech, AVEO Pharmaceuticals, Celladon, Cerulean, Constellation Pharmaceuticals, CymaBay Therapeutics, Fate Therapeutics, Hua Medicine, Infinity Pharmaceuticals, Intarcia Therapeutics, Ironwood Pharma, Juno Therapeutics, QuatRx Pharmaceuticals, Receptos, Vitae Pharmaceuticals, City (cities) where offices are located: Boston (6); South San Francisco, CA; Gainesville, FL; Munich, Fund size and status: More than $2.6 billion committed capital under management across five funds, Current fund: Approximately $300 million MPM BioVentures V L.P., closed 2010 (7), Current biopharma portfolio companies: 23andMe, Amphivena Therapeutics, Anthera Pharmaceuticals, Aratana Therapeutics, Astute Medical, Celladon, Cerecor, Chiasma, Conatus Pharmaceuticals, Epizyme, Iconic Therapeutics, Mitokyne, Proteon Therapeutics, Radius Health, Rhythm Pharmaceuticals, SAI, Selexys Pharmaceuticals, Sideris Pharmaceuticals, Solasia Pharma, Syndax Pharmaceuticals, Theraclone Sciences, True North Therapeutics, Vascular Pharmaceuticals, Verastem, City (cities) where offices are located: Princeton, NJ, and San Diego, Fund size and status: More than $2.7 billion under management across eight funds, Current fund: $500 million Domain Partners VIII, closed 2009, Current biopharma portfolio companies: Achaogen, Achillion Pharmaceuticals, Adynxx, Afferent Pharmaceuticals, Aldeyra Therapeutics, Alimera Sciences, Applied Proteomics, Ariosa Diagnostics, Ascenta Therapeutics, Asmacure, Astute Medical, Atara Biotherapeutics, aTyr Pharma, BioNano Genomics, Cantex Pharmaceuticals, Celator Pharmaceuticals, Clovis Oncology, CoDa Therapeutics, CoLucid Pharmaceuticals, Dicerna Pharmaceuticals, Domain Elite Holdings, Domain Russia Investments, Eddingpharm International Holdings, Epic Sciences, Esperion Therapeutics, Evoke Pharma, Five Prime Therapeutics, IntegenX, Marinus Pharmaceuticals, Meritage Pharma, NovaDigm Therapeutics, Ocera Therapeutics, Oraya Therapeutics, Orexigen Therapeutics, Otonomy, ProteinSimple, Regardo Biosciences, Sera Prognostics, Syndax Pharmaceuticals, Tobira Therapeutics, Tragara Pharmaceuticals, VentiRx Pharmaceuticals, Veracyte, Zogenix, Fund size and status: $2.8 billion under management across 10 funds, Current fund: $650 million InterWest Partners X, closed 2008, Current biopharma portfolio companies: Applied Genetic Technologies (AGTC), Alvine Pharmaceuticals, Arcion Therapeutics, Carbylan Therapeutics, Cebix, Centrexion, Cidara Therapeutics, Drais Pharmaceuticals, Eiger BioPharmaceuticals, Lycera, MacroGenics, Ocera Therapeutics, On Demand Therapeutics, Paratek Pharmaceuticals, PMV Pharma, QuatRx Pharmaceuticals, RadioRx, Tesaro, Trius Therapeutics, USDS, Xenon Pharmaceuticals, City (cities) where offices are located: Cambridge, MA. It connects accredited investors with The financial-services giant, based in Boston, is better known for handling people's personal investments and stock trading. The firm seeks to invest in seed-stage, early-stage and later-stage companies. The firm seeks to invest in the software as a services (SaaS), cloud, data science, and artificial intelligence sectors. , which conducts research and development of pharmaceuticals related to COVID-19. See: http://blogs.wsj.com/venturecapital/2014/04/04/refocused-mohr-davidow-ventures-is-raising-a-new-fund/ Founded in 2013, LiveOak Venture Partners is a venture capital firm headquartered in Austin, Texas. Asia Pacific ; AUM: $28B. Below is this years GEN list of 20 top venture capital firms, and broader financial firms that invest venture capital or other equity in early- to late-stage biotechnology and pharmaceutical companies, ranked by total capital under management or, for some firms, total active committed capital from funds in use. Founding Partners Carl Soderstrom and Clay Heighten, MD. Special-purpose acquisition companies, or SPACs, were not factored into the equity holdings because of different disclosure requirements but were noted in our assessment of the VCs. This company specializes in life science and provides investments for start-ups and growing businesses. The firm seeks to invest in early-stage breakthrough technologies. The firm plans to deploy $500 million to $700 million in capital in 2022, a spokesperson said. Six top firms held more than $1 billion in equity: Arch Venture Partners, Novo Holdings, Flagship Pioneering, RA Capital Management, Perceptive Advisors, and SoftBank. Find the right companies, identify the right contacts, and connect with decision-makers with an all-in-one prospecting solution. Partners Jim Kim, Amit Mehta, Alex Kinniier, Jocelyn Doe, Mark H. Goldstein, and Mark Blackwell. Founded in 2005, S3 Ventures is a venture capital firm based in Austin, Texas. Octopus Ventures is a London and New York based venture capital firm, focused on backing unusually talented entrepreneurs. (12), Current fund: 250 million ($310 million) Highland Capital Growth Fund, closed in May; and the $400 million Highland Capital Partners IX L.P., closed 2013. The firm seeks to invest in the software, advanced manufacturing, big data, cybersecurity, digital health, Internet of Things, mobile, Software-as-a-Service, agriculture, real estate, construction, and industrials sectors. With the global venture capital investment market size reaching US$ 233.9 Billion in 2022, you might be wondering who the industry's biggest players are. Venture capital financing, Private equity, The Best Original Streaming Shows Of The Last Few Years. (1), Current biopharma portfolio companies: Adamas, Balance Therapeutics, CardioDx, Crescendo Bioscience, DVS Sciences, Pacific Biosciences, Personalis, RainDance Technologies, Sequenta, City (cities) where offices are located: Seattle and Menlo Park, CA, Fund size and status: More than $2 billion under management across seven funds, Current fund: $377 million Frazier Healthcare VII, closed 2013, Current biopharma portfolio companies: Achaogen, Alcresta, Allena Pharmaceuticals, Amicus Therapeutics, Anaptys, Attercor, Cadence Pharmaceuticals, Chimerix, Cidara Therapeutics, Collegium Pharmaceutical, Portola Pharmaceuticals, QuatRx Pharmaceuticals, Rempex Pharmaceuticals, Semnur Pharmaceuticals, Silvergate Pharmaceuticals, Tobira Therapeutics, VentiRx Pharmaceuticals, #14 (tie). 4 On July 1, the firm submitted a Form D stating that its partners had raised $221.5 million toward a planned ninth fund of $750 million, to be named Esssex Woodlands Fund IX. The funds focus on the emerging science of individual health and through health the delivery of happiness. Fund size and status: More than $14 billion in committed capital across 14 funds, Current fund: $2.6 billion New Enterprise Associates 14 L.P., closed 2012, Current biopharma portfolio companies: 3-V Biosciences, Acadia Pharmaceuticals, Adaptimmune, Alimera Sciences, Amicus Therapeutics, Ardelyx, Blend Therapeutics, BrainCells, Cadence Pharmaceuticals, Cardioxyl Pharmaceuticals, Cerecor, Cleave Biosciences, Clovis Oncology, Cydan, Dermira, Edimer Pharmaceuticals, Envisia Therapeutics, Epizyme, Galera Therapeutics, Glycomimetics, Hydra Biosciences, Hyperion Therapeutics, Intarcia Therapeutics, Intrinsic Therapeutics, Liquidia Technologies, Loxo Oncology, Lumos Pharma, Mersana Therapeutics, Mirna Therapeutics, Nexchem, NexImmune, Novast Holdings, Predictive Biosciences, Prosensa, Proteostasis Therapeutics, Psyadon Pharmaceuticals, Ra Pharma, Rhythm Pharmaceuticals, Rigel Pharmaceuticals, Roka Bioscience, Satori Pharmaceuticals, Sunesis Pharmaceuticals, Supernus Pharmaceuticals, Targacept, Tesaro, Transcept Pharmaceuticals, Tracon Pharmaceuticals, Trevena, Zyngenia, 1 The firm was ending investments in life sciences, and raising a fund in the $200 million range, according to an April 4 news report in Venture Capital Dispatch, a blog of The Wall Street Journal, in which the firm declined comment. The year 2021 is closing with a biotech investment rush as Eir Ventures, Apollo Health Ventures, and Mercks venture capital arm M Ventures raise impressive funds to speed up life sciences innovation. Boost Heroes New startups with unique concepts are developing as the Global Biopharma and MedTech Industries experience unprecedented growth. Business Products and Services (B2B), Healthcare Technology Systems, Information Technology, Founder & Managing Partner Leonard Lenny Saizan Jr. Texas Halo Fund is an investment firm based in Houston, Texas. This years list shows the upward progression of VC firms; the lowest-ranked of this years firms had $1.25 billion under management, compared with more than $1.1 billion for the Top 30 Venture Capital Firms of 2013. It is noteworthy that the company identifies various affiliate investment companies, or New River Management Funds, which are smaller corporate venture capital funds with a regional concentration. Largest investment: 16.2 million shares of Theseus Pharmaceuticals worth $259 million at the time of its IPO, Total holding value of 2021 IPOs: $988.4 million. 11 On Nov. 14, the firm submitted a Form D filing stating that partners were raising funds toward a ninth fund, to be named Bessemer Venture Partners IX Institutional. The firm prefers to invest in companies from the software, blockchain, robotics, software-as-a-service, artificial intelligence, and machine learning sectors. OrbiMed invests across the global healthcare sector, from early-stage venture capital to sizable publicly-listed enterprises. WebInsider analyzed more than 90 IPOs to find the top venture-capital firms that led biotech in 2021. It is a part of the more prominent Novo Holding company, whose investments are more varied. , Mark H. Goldstein, and connect with decision-makers with an all-in-one prospecting solution individual health and health., Mark H. 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