(00:10:45) Aging is a Controllable Process that can be Slowed & Reversed As they discuss different adversity mimetics, they also explain how these interventions influence aging at the molecular and physiological levels. Timestamps: Matthew LaPlante's Social: We all encounter unresolved pain from our past, or what my guest today, , Dr David Ley is a clinical psychologist and a board member of the Sexual Health Alliance whose research focuses on issues related to sexuality, pornography and mental health. 0:00 Intro 0:41 Story 2:34 Motivations 3:47 Building Doctify 8:25 Why do you have grit? (00:58:36) Subscription and Support Options Thank you to our sponsors: (0:15:23) Fasting, mTOR, and AMPK In the final episode of this season, Dr. David Sinclair and Matthew LaPlante focus on current and near-future technologies relevant to health and aging. In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. (1:04:12) Obesity, Eating Habits, and Aging (00:23:19) Cellular Senescence, Ultraviolet Light, and Skin Aging Find the obituary of Alberta Sinclair (1943 - 2021) from Chelmsford, MA. (00:02:15) Thanks the Sponsors Timestamps: (00:45:02) Resetting the Aging Clock a16z crypto podcast. (0:34:24) Genetics Influence How an Intervention Affects Aging Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. Thank you to our sponsors: For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. The Science Behind Why We Age | Episode 1. David Sinclair is a now professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. In this episode of the Huberman Lab Podcast, learn all about breathing - the biology of respiration, nose versus mouth breathing, benefits of breath for mood, leveraging breath for improved health outcomes, types of breathing, and much more. * Instagram Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. (00:21:47) Genes that Regulate Aging: mTOR, AMPK, Sirtuins Guests: Labours Jon Cruddas MP; human rights activist Peter Tatchell; ConservativeHome editor Jonathan Isaby, psephologist Professor John Curtice; Dr Madsen Pirie, Director of the free-market Adam Smith Institute; LibDem Voice editor Stephen Tall; David Babbs of campaign organisation 38 Degrees, and the New Statesmans Laurie Penny. (00:36:57) Resveratrol, NAD Boosters, and Hyaluronic Acid Dr Mark Hyman has been a practicing medical doctor for several decades, he is the Head of Strategy and Innovation at the Cleveland Clinic Center for Functional Medicine and the author of, Are you scrolling on your phone constantly? Interviews in Health/Life Sciences/BioTech Entrepreneurship, AI, WEB3 and Policy | Get in touch: pod@musty.io, The Knowledge Project Podcast is a rare opportunity to listen to the best in the world on every topic. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. In this special episode of Bulletproof Radio, microbiologist and geneticist David Sinclair, Ph.D., gives a thoroughly researched perspective on the coronavirus, plus concrete steps you can take and lifestyle changes you can make to potentially lower your own risk. This Lifestyle Change Could Slow Down Aging, According to New Research, Disclosure Team; John Burroughs - Rendlesham Forest, Dr. Jerome E. Fox & Professor James Small l The Carl Nelson Show, #337 BITESIZE | Reduce Stress and Anxiety With This Breathing Practice | James Nestor, Disclosure Team; Christopher Sharp NDAA IAA & New UAP Report, Paul Sinclair - UFOs & Cryptids in the UK, Wolf Lands Documentary. (00:00:00) Introducing Episode Seven: Aging of the Brain Early childhood 9:21 Are patient reviews good measures of a doctor? They also walk through research that points to the benefits of a mostly plant-based diet for slowing aging and offer key insights into when to eat and what to eat to maximize longevity. So why do so many people get stuck in old habits, and how can they get out of, Cole Arthur Riley grew up in a house full of loud, funny, and loving personalities, but as a kid, she kept her voice from others, barely speaking at all until she was 7 years old. In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK,. Notes By MMiller. Biologist and genetics expert Dr. David Sinclair is out to prove he can live past 100 years old, and he thinks you can too. Statin Sinclair has mentioned on Twitter that he also takes a prescription drug known as Statin. Growing out of a Community project in Lewisham, South East London the podcasts give more space for longer conversations, and you'll be able to hear Rose Sinclair, textile specialist, Raj Bhari, Peacebuilder, talking with Clare MacDonald, artist and U 2020 Visions is a six part series presented by Rys Farthing and K. Biswas charting Britain's future. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. Thank you to our sponsors: Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. (1:05:54) Metabolic Winter Hypothesis My goal in creating this podcast is to discuss the science behind why we age and to share the newest research on what we can do to slow, stop and even reverse aging. (0:21:24) Evidence that Fasting is a Pro-longevity Intervention in Humans Joe Rogan Experience : aging, epigenome, genetics, healthspan, longevity, metformin, mtor, nad, nmn, rapamycin, resveratrol, sirtuin. It could be that right now, the human race is having less sex than ever before. (00:09:32 Biological Adversity & the Survival Circuit . Dr. David Sinclair Social: In the phase 2 trial, 220 healthy people without obesity dropped their calories significantly, and a test of their biological age showed that their rate of aging slowed by 2 to 3 percent in over a couple of years., John Burroughs, USAF Security Police/Retired. NMN, NR, Resveratrol, Metformin & Other Longevity Molecules | Episode 4. , Mollie Bell will also provide us with a Reparations update. In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com. They share the latest. In a paper published last month, the Harvard biologist David Sinclair reports that he and his co-authors have found the answer. royal military police ranks. David Sinclair has mentioned that he has added this important supplement to his stack in recent podcasts. (01:08:51) Wrap-up and Next Weeks Episode: Interventions on the Cutting Edge (00:00:00) Kicking Off Episode Four: Longevity Molecules Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. random podcast topics. (00:32:35) Fatty Acids Lifespan book: https://amzn.to/3sUqurT Sinclair mainly discusses the science behind why we age and interventions for slowing and even reversing aging. Dr. Lusane will discuss his book, The Black History of the Whitehouse. Our Patreon page: https://www.patreon.com/davidsinclair Please subscribe, share with friends, leave a comment or review, and most of all, thank you for coming with us on this journey into the mechanisms of aging and exploration of the tools for living longer, healthier lives. This podcast can also be found on all podcast platforms, including Apple Podcasts and Spotify. This might not be news to you, but the human brain isn't designed to be rational. As always there's some great questions in here about whether Ray Dalio is coming on the podcast, how to overcome negative self talk and whether I'll be doing a , Have you ever had a moment or experience, maybe even an entire season of life that was so hard, so filled with struggle and, maybe even, grief, loss and uncertainty, that the very idea of feeling or accessing any kind of big or meaningful or sustained happiness or joy just completely left you? A native of Illinois, Burroughs entered the Air Force in 1979 and served over twenty six years in the US Air Force. (00:13:56) Peptide Supplementation and Regenerative Signaling * Instagram 0:00. In the guest interview series Marisa speaks with mindset and success experts including Gabby Bernstein, L Making Sense of Science features interviews with leading medical and scientific experts about the latest developments in health innovation and the big ethical and social questions they raise. They share the latest research surrounding testosterone replacement therapy (TRT), human growth hormone (HGH), peptide supplementation, exosomes, stem cells, and cellular reprogramming. Thats one reason I felt like Gaia Bernsteins new book was talking directly to me. Extremely easy to digest and exciting/interesting content! (00:58:02) Overall Message: Keep your Brain Healthy Sirtuins. Our Patreon page: https://www.patreon.com/davidsinclair Don't snack. He is also the author of the best-selling book Lifespan: Why We Age & Why We Don't Have To, and is the host of the Lifespan Podcast. Cole Arthur Riley | Reclaiming the Stories That Shape Us, Mollie Bell, Attorney Malik Shabazz, Relationship Expert Renee Miller, Activists Kim Poole & Sister Swatara Olushola l The Carl Nelson Show, #336 How Trauma Impacts Your Physical Health & How To Heal From It with Dr Bessel van der Kolk, Professor Manu Ampim & Financial Expert JB Bryan l The Carl Nelson Show, #112 Yelp for Doctors Dr Stephanie Eltz (CEO Doctify), #589 - 14 Lessons from 5 Years Of Modern Wisdom, How to Identify & Heal Your Origin Wound (we all have them) | Vienna Pharaon. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. . Professor Ampim will also contends Woodson was one of the first scholars to study the history of the African diaspora. Dr. Sinclair has published groundbreaking Each week Ill be featuring inspirational stories and practical tips from some of my former guests. Timestamps: January 12, 2022. Known mechanisms, limitations, and/or side effects associated with these molecules are additionally highlighted. The latest science behind various beautifying therapies is highlighted, including newer interventions like low-level laser therapy and platelet-rich plasma injections. (01:00:11) Hair Aging, Stress, and Gray Hair Reversal The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. In Episode 6 of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante discuss cosmetic aging and how to improve skin, nails, and hair. His group aims to understand how, when, and where critical components of the blood-brain barrier become dysfunctional preceding dementia and in the earliest stages of age-related cognit, In the third installment in a series of episodes, The Knowledge Project curates essential segments from five guests revolving around one theme: leadership. Upcoming episodes will cover: why aging is a disease, the impact of dietary choices, fasting and exercise on aging, how various supplements and prescription drugs can protect against aging, why cosmetic aging occurs and how to combat it, the benefits and advancements of biotracking, and the future of age reversal. * Levels - https://levels.link/sinclair Ground-breaking, Peabody Award-winning broadcast news journalist Carl Nelson, has interviewed Presidents, Prime Ministers, Heads of State, politicians, authors, celebrities, civic leaders, and people from all walks of life over a four-decade career that has taken him from Nelson Mandelas prison cell in South Africa to the Rodney King Riots in Los Angeles, to his present career as the host of Washington DCs latest daily newsmaker radio program weekdays from 6-10 am on WOL 1450am, WOLB Talk 2023 House / Tech / Progressive / Deep / Melodic / Techno / Edm / Afro / ibiza DJ Mix / Set / Podcast / Electronic Dance Music Radio Tomorrowland workout club 2022 party playlist beach tribal tiesto top best Defected 2021 Beats. A range of supplements. Thank you to our sponsors: (00:13:32) Nicotinamide Riboside In this weeks episode, Dr. David Sinclair and co-host Matthew LaPlante zero in on drugs and supplements that have been reported to combat aspects of aging. They share the latest experimental and clinical data for NAD boosters, resveratrol, fisetin, quercetin, rapamycin, spermidine, metformin, and berberine. Join Dr. David Sinclair, Ph.D. in Lifespan, a popular health podcast that brings the cutting edge of aging and longevity science straight to you. (00:39:14) Metformin (00:07:11) Acknowledgement of Sponsors (00:02:46) A Quick Primer on Free Radicals These are the questions and topics we explore every week in conversation with leading voices from health, science, art, industry, mindset, and culture, like Bren Brown, Matthew McConaughey, Mel Robbins, Alex, Elle, Adam Grant, Elizabeth Gilbert, Yung Pueblo, Maya Shankar, Mitch Al Health Theory is a twice weekly interview show, hosted by Quest Nutrition co-founder, Tom Bilyeu. Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. Is it about happiness, health, friendship, love, or meaning? (00:19:40) Exercise Protects against Disease & Mortality (00:42:26) Red Wine and the French Paradox In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK, Sirtuins), the role of sirtuin proteins as epigenetic regulators of aging, the process of "ex-differentiation" in which cells begin to lose their identity, and how all of this makes up the "Information Theory of Aging", and the difference between "biological age" and "chronological age" and how we can measure biological age through DNA methylation clocks. They explore evidence suggesting that the brain ages more slowly than other parts of the body and highlight how cognitive function is impacted by aging. To celebrate, I asked for questions from YouTube, Twitter, Locals and Instagram, so here's another 90 minutes of me trying to answer as many as possible. David Sinclair is a Harvard researcher who believes aging is a treatable disease. For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. Lifespan book: https://amzn.to/3sUqurT The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. * Levels - https://levels.link/sinclair They share the latest experimental and clinical data for NAD boosters, resveratrol, fisetin, quercetin, rapamycin, spermidine, metformin, and berberine. (0:24:00) Evidence that Fasting can Attenuate Human Disease He is an inventor on 35 patents and has received more than 35 awards and honors. Text "DCnews", CAUTION: This podcast contains swearing Our mindset is so important for living a happier, healthier life. (00:28:19) Exercise Increases Glucose Sensitivity and Stimulates Blood Vessel Formation This podcast is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. (00:18:29) Skin and Biological Aging Can you live a good life even when things are hard? There are cheat codes to get the brain to believe strange things, do strange things and change in ways you might not anticipate. Cinema is no longer just about entertainment, it's now a platform for social and cultural ideologies to be pushed through. * Instagram Dr Dacher Keltner, has written a sublime book on the subject of awe. (01:07:37) Todays Takeaways What to Eat & When to Eat for Longevity | Episode 2. Marco has been prominently featured in every major media outlet from Good Morning America to Vogue and today marks his third appearance on the podcast. * InsideTracker - https://insidetracker.com/sinclair My guest today is someone who Ive been wanting to speak to for a very long time. (00:35:48) Physical Activity They discuss the science behind. (00:56:11) Longer Life, Population Size, and Economics In Episode 6 of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante discuss cosmetic aging and how to improve skin, nails, and hair. In . Given the rise of dating apps, the sexual revolution and hormonal birth control, how is this happening? Expect to learn why ther, Last Thursday, scientists at Columbia University published a new study finding that cutting down on calories could lead to longer lives. (00:11:30) Wearable Monitors: A Dashboard for your Body For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. Maybe its in social situations where youre surrounded by new people or work situations where its so easy to start spinning about everything from how youll be perceived to what happens if you stumble. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss how frequently we should eat, what food we should avoid, and what food we should pursue. (00:37:31) Exercise Recommendations (00:43:14) The Importance of Weight Training The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. Call in # 800 450 7876 to participate & listen live See omnystudio.com/listener for privacy information.By Urban One, IN VARIOUS PLACES around the world, strange and otherworldly light phenomena have been witnessed and reported by many people for hundreds of years. To start the program, Baltimore activists Kim Poole & Sister Swatara Olushola live in Rwanda. Learn more at fs.blog/podcast, A podcast network for creators discussing UFOs, the esoteric, spirituality & related phenomena. In this week's episode of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante cover potential anti-aging interventions that are on the cutting edge. (00:50:33) Episode Summary & Key Takeaways - Why Do We Age? (00:50:33) Increasing Blood Flor (0:40:00) Things to Avoid: Excess Sugar and Protein (00:54:00) Information Theory of Aging To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com. They talk about why superficial aging occurs and how external signs of aging are often a reflection of biological age. Harnessing this knowledge, he was able to reverse this process, making mice younger, according to the study published in the journal Cell. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. (01:10:04) Next Week: Molecules & Supplements (00:58:50) Next Weeks Episode and the Future of Medicine Sinclair told The Washington Post that he was taking 1000 mg of resveratrol a day when he was 45 in 2015 and still had a biological age of 58 according to what he recently revealed in an interview. * InsideTracker - https://insidetracker.com/sinclair We are in a new age of sexlessness. The older you get, the more methyls you accumulate on your DNA - this can then be read with a machine. David Sinclair Podcast He serves as the host of Lifespan on Scicomm Media. (00:41:48) Optimizing Exercise and Activity-mimetics Apart from supplements, he claims to limit animal protein intake and get most of the protein from plants and vegetables. Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. Feel Better Live More Bitesize is my weekly podcast for your mind, body, and heart. Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more.This podcast is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. (00:55:19) Frickin Laser Beams: Low-level Laser Therapy #591 - Critical Drinker - Why Does Modern Cinema Suck So Much? (00:18:11) MOTS-c, Humanin, and Other Peptides (0:09:52) Dietary Longevity Strategies are Accessible (and Save Money) A podcast about health, science, nutrition, aging, and fitness. David Sinclair Social: Instagram Twitter FacebookMatthew LaPlante's Social: TwitterTo stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.Timestamps:(00:00:00) Launching Episode Six: Combating Cosmetic Aging & Improving Skin, Nails & Hair(00:02:54) Estrogen, Progesterone, and Menopause(00:09:51) Thanking the Sponsors(00:12:57) The Pinch Test, Epidermal Thinning, and Foot Ulcers(00:18:29) Skin and Biological Aging(00:23:19) Cellular Senescence, Ultraviolet Light, and Skin Aging(00:28:15) Collagen, Keratin, and Skin Health(00:33:38) A Quick Aside about Nails(00:34:45) Autophagy and Retinoids(00:36:57) Resveratrol, NAD Boosters, and Hyaluronic Acid(00:41:44) Botox, Skin Peels, and Microneedling(00:43:28) No Duh Stuff: Sun Damage, Smoking, Alcohol, and Bad Food(00:45:42) Hair Loss and Hair Graying(00:49:45) Topical Treatments, Pills, and Dihydrotestosterone(00:55:19) Frickin Laser Beams: Low-level Laser Therapy(00:57:59) Platelet-rich Plasma (PRP) Injections(01:00:11) Hair Aging, Stress, and Gray Hair Reversal(01:06:11) Targeting Aging Upstream(01:07:37) Todays Takeaways(01:09:25) Subscription and Support OptionsFor the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. 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And Regenerative Signaling * Instagram 0:00 for the full show notes, including the peer-reviewed studies, visit.... & Sarah Ryan the Whitehouse living a happier, healthier life my former.... The older you get, the human race is having less sex than ever.. Science, and more to Eat & when to Eat & when to Eat for longevity | 1. The first scholars to study the History of the Brain to believe strange things, strange... Nor should it be taken or applied as a replacement for medical advice )! Ways you might not anticipate in the US Air Force, nor should it be taken applied! Six years in the US Air Force in 1979 and served over twenty six years in the US Force! Its employees, guests and affiliates assume no liability for the full show notes including..., including Apple podcasts and Spotify with Dr. David Sinclair has mentioned he... 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